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Genomics Expertise
We offer state-of-the-art expertise in the forefront of sequencing technology developments.
read moreGenomics Expertise
Areas of expertise
- DNA isolation
- DNA biobanking
- High throughput sequencing using targeted strategies (like PCR, hybridization or MIP-based target enrichment both for Sanger and next generation sequencing)
- Genome wide sequencing strategies using next generation sequencing (non-invasive prenatal testing, exome and genome).
News and Events
27-03-2024
With the arrival of the 2nd Revio, we are offering our long-read sequencing services to external parties. On Tuesday, March 19, we organized an event in collaboration with PacBio, “Radboud PacBio Day". See LinkedIn for an impression of this event.
17-04-2023
Reportage NRC handelsblad: 'Is het een schimmel, is het een virus? Sequencers profileren ziektekiemen razendsnel' hierin vertelt o.a. bio-informaticus Jordy Coolen over het sequencen op de apparaten van ons technology center.
22-12-2022
PacBio long-read sequencing in collaboration with the Senckenberg Research Institute and Natural History Museum
Genome assembly is a valuable resource for future conservation of species that are threatened by extinction. NGS technologies have become globally established for the study of systematic-phylogenetic issues. We collaborate with the Senckenberg Research Institute and Natural History Museum and facilitate PacBio long-read sequencing.
If interested read these recent publications and/or contact us at gtc@radboudumc.nl :
- Chueca et al. De novo Genome Assembly of the Raccoon Dog (Nyctereutes procyonoides). Front Genet. 2021 Apr 29;12:658256. PMID: 33995489.
- Blumer et al. Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding. Sci Adv. 2022 Mar 25;8(12):eabm6494. PMID: 35333583.
- Merges et al. Virus diversity in metagenomes of a lichen symbiosis (Umbilicaria phaea): complete viral genomes, putative hosts and elevational distributions. Environ Microbiol. 2021 Nov;23(11):6637-6650. PMID: 34697892.
- Winter et al. A Chromosome-Scale Genome Assembly of the Okapi (Okapia johnstoni). J Hered. 2022 Oct 21;113(5):568-576. PMID: 35788365.
07-11-2022
PacBio long read amplicon sequencing
In our recent study by Daan Viering et al, PacBio long read amplicon sequencing identified 46 previously undetected exonic and intronic variants in 95 pre-screened patients with suspected Gitelman syndrome. This paper highlights that intronic pathogenic variants explain an important part of the missing heritability in Gitelman syndrome, and shows the advantage of long read amplicon sequencing for the detection of these so far hidden variants.
13-10-2022
Minister Ernst Kuipers brengt werkbezoek aan het Genomics Technology Center
Op woensdag 12 oktober heeft minister Ernst Kuipers van het Ministerie van Volksgezondheid, Welzijn en Sport een bezoek gebracht aan ons Technology Center.
Meer informatie over het werkbezoek
Genome diagnostics
We perform prenatal as postnatal genetic diagnostics. We offer diagnostics to a large number of hereditary and innate conditions.
read moreContact us
GTC@radboudumc.nl
Tel: +31 (0)24 3617891
Postal address
Attn. Janneke Weiss
Genome Technology Center (Route 848)
Radboud University Medical Center
Geert Grooteplein Zuid 30
6525 GA, Nijmegen
The Netherlands
Instruments and equipment
• Novaseq X Plus (Illumina)
• NovaSeq6000 (Illumina)
• NextSeq500 (Illumina)
• MiniSeq (Illumina)
• Revio (Pacific Biosciences)
• Sequel IIe (Pacific Biocsciences)
• Stratys (Bionano)
• Saphyr (Bionano)
• GridION (Oxford Nanopore)
• ABI 3730XL analyzer (ThermoFisher)
Instruments and equipment
In our lab we have a variety of instruments and equipment available.
• 1x - Novaseq X Plus (Illumina)
• 3x - NovaSeq6000 (Illumina)
• 2x - NextSeq500 (Illumina)
• 2x - MiniSeq (Illumina)
• 2x - Revio (Pacific Biosciences)
• 2x - Sequel IIe (Pacific Biosciences)
• 1x - Stratys (Bionano)
• 2x - Saphyr (Bionano)
• 1x - GridION (Oxford Nanopore)
• 2x - ABI 3730XL analyzer (ThermoFisher)
Our experts
