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Antimicrobial Stewardship and Infection Prevention

We focus on to the development and implementation of (cost)effective, timely, safe, and person-centered diagnostics, antimicrobial therapy and infection prevention measures for patients with -a risk of- an infectious disease. We are committed to improve patient care safely in order to achieve the best patient outcomes.

With the ultimate aim of curbing antimicrobial resistance, the research focus is on everyday patient problems - both in high and low resource settings - to have global impact. Providing the evidence for appropriate patient care.

Antimicrobial resistance (AMR) is considered a global health threat as infections become more difficult to treat. There are two cornerstones of reducing the development of AMR: Antimicrobial Stewardship and Infection Prevention. The Radboudumc Community for Infectious Diseases (RCI) has always played an important role in the area of AMR, both nationally and internationally.

Our research focuses on the following main questions:

1. What innovative diagnostic, antimicrobial therapy or infection prevention measure improves patient outcomes, reduces costs and/or limits the development of antimicrobial resistance?
2. How can these evidence-based interventions be implemented into daily practice?

Innovative diagnostics, antimicrobial therapies and infection prevention measures

This research represents the development and clinical testing of innovative diagnostics, antimicrobial therapy or infection prevention measures. This ‘man’-based research provides scientific evidence for the added value of the tested interventions.

Implementation of evidence-based interventions into daily practice

This behavioural research aims at the development and testing of innovative implementation strategies to introduce evidence-based interventions in daily practice. We explore the gap between evidence and practice and its determinants. The latter information is crucial when designing implementation strategies aimed at improving care. This ‘population’-based research provides scientific evidence for the added value of the tested improvement interventions.

International Health

The Radboudumc Community for Infectious Diseases offers a range of activities for international health and tropical infectious diseases in which education, research and service are integrated. These activities are established in 1972.

We maintain working relations with several groups within the Radboud University as well as with many other universities in the Netherlands. We have established long-term working relations with specific institutes in Latin America, Africa and Asia. 

Education: Rotation Program for Student Doctors in low-income countries

At the end of the Master study program, a student can choose to participate in the Rotation Program for 3 months for Student Doctors in low-income countries (Africa, Asia, Latin America). In view of the adaptability that is demanded and to ensure a good cost-benefit outcome, the student will be well prepared before leaving for the rotation. When a student has participated in this program, this will be stated in his or her medical qualifications.  More information

Research

International health research is an integral part of RCI. Long-term relations have been established with different partners in the tropics. Research lines include tuberculosis, HIV, malaria, dengue, antimicrobial resistance. 

Service

Service on tropical diseases and travel medicine is provided by internist-infectious diseases specialists with long-term experience in tropical medicine and travel medicine. Specialized microbiological diagnostic facilities are also available. The Radboud Travel Clinic provides travel advice to the general public, but also to individuals with chronic diseases.    

Team 

Within RCI we have a core team of senior academic staff-members. Each with several years of field experience in public health or tropical medicine. In addition junior staff is employed for specific projects.