Finding early diagnostic indicators that can accurately identify patients with localized tumors who benefit from (minimally invasive) treatment while avoiding unnecessary biopsies and treatment;
Developing and evaluating new treatment and diagnostic modalities with better efficacy and less mutilating effects;
Finding pre- and on-treatment biomarkers that can identify or early discriminate patients who are expected to respond to specific therapies;
Identifying host–related risk factors as leads for primary and tertiary prevention;
Optimize the risk-benefit ratio of available anticancer drugs through early identify.