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About
We create novel biomaterial-based therapies for regeneration of hard tissues. Overall, we aim to decipher which physicochemical properties of biomaterials are able to trigger the natural self-healing capacity of hard tissues.
Aims
We strive to overcome major shortcomings of conventional biomaterials by smart design of biomaterials with improved biological, mechanical and handling properties. To this end, we synthesize a wide range of nano- and microstructured biomaterials including injectable and biodegradable hydrogels and cements, colloidal and self-healing composites, barrier membranes and coatings, as well as nanoparticles for nanomedicine-based approaches. These biomaterials are functionalized with various types of drugs and/or patient-derived cells to maximize their capacity to stimulate regeneration for both healthy and diseased patients.
More specifically we aim to:
- Design novel colloidal self-healing biomaterials for treatment of bone diseases
- Develop novel bone/tooth-on-chip devices and human ex-vivo models for bone regeneration
- Develop novel surface modification techniques to improve soft tissue integration of oral implants
