About this project

Human functional genomics project is based on integrating multi-layers of molecular data to help understand disease mechanisms better. This systems approach enable us to identify novel targets and/or validate existing targets. 

Cohorts of healthy volunteers: 

  • cohorts of healthy individuals with different genetic backgrounds: 
  • Western-European Netherlands (3 cohorts done: n=500, 200, 1600) 
  • Eastern-Europeans Romania (inclusion started 2017) 
  • Eastern-Africans Tanzania (n=300 completed) 
  • Asians Indonesia (pending funding 2019) 

 

Cohorts of patients: 

  • candidemia (330 completed) 
  • sepsis (started 2017) 
  • thyroid cancer (started end 2016) 
  • bladder cancer (started 2017) 
  • rheumatoid arthritis (n=400 completed) 
  • recurrent Vulvo-vaginal Candidiasis (started 2017) 
  • obesity +/- cardiovascular diseases (300 completed) 
  • Gout (started June 2016) 
  • type 1 diabetes (200 completed) 
  • BCG vaccination cohort (n=300, 3 time points, started 2017) 
  • Crohn’s disease (to start end 2018) 
  • HIV (200 completed) 
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Radboudumc and partners Collaboration opportunities The Human Functional Genomics Project

About this project

Human functional genomics project is based on integrating multi-layers of molecular data to help understand disease mechanisms better. This systems approach enable us to identify novel targets and/or validate existing targets. read more

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News

15 Million Euro to discover new avenues to fight the HIV virus

17 February 2021 André van der Ven, Mihai Netea and colleagues, received 15 mEuro from the pharmaceutical company ViiV Healthcare to discover new avenues to fight the HIV virus.

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