NWO grant for a tissue-generating patch - To close diaphragmatic defects

21 August 2019

Willeke Daamen and Toin van Kuppevelt (Dept. of Biochemistry), theme Reconstructive and regenerative medicine, and Dirk Grijpma and André Poot (University of Twente) were recently awarded a 690 k€ grant by the Netherlands Organisation for Scientific Research (NWO, domain Applied & Engineering Sciences) for the development of advanced patches for closure of diaphragmatic defects in children with congenital diaphragmatic hernia.

Biodegradable patches with a radial pore structure composed of hybrids of artificial and natural polymers will be developed and coated with basement membrane components to enhance diaphragm regeneration.

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