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A recent study published in Influenza and Other Respiratory Viruses on January 8, 2025, led by Marco Del Riccio and a team of collaborators, offers insights into influenza vaccination trends during the COVID-19 pandemic across 12 countries. The findings indicate that while vaccination rates rose in 2020, these increases were not consistently sustained in subsequent years, representing a missed opportunity to capitalize on pandemic-driven awareness.
Researchers from Radboudumc, the University of Florence, and Nivel analyzed vaccination trends spanning 2012 to 2023, using data from national health organizations and international sources. Their focus was on vaccination rates among older adults aged 65 and above. Employing advanced statistical methods such as segmented regression models and polynomial regression models, the team explored whether 2020 marked a significant shift in vaccination trends and compared observed rates post-2020 with predictions based on pre-2020 data.
The results showed that in 2020, 10 out of 12 countries experienced an increase in vaccination coverage rates among the elderly. However, statistically significant changes were observed only in Spain and England. By 2021, most countries returned to pre-pandemic levels, with Spain standing out as the exception, maintaining higher vaccination rates.
Seasonal influenza remains a significant global health challenge, causing substantial morbidity and mortality, particularly among high-risk groups such as the elderly, children, and individuals with chronic conditions. Vaccination is a critical strategy to mitigate this burden, yet global coverage rates often fall short of recommended levels. The COVID-19 pandemic in 2020 created a unique moment to raise awareness about respiratory health risks, driven by intensified public health campaigns and heightened concern over respiratory illnesses. This study, conducted under the FluCov project, sought to assess whether the temporary increase in vaccination rates observed in 2020 persisted in the following years.
Next steps
The study underscores the importance of sustained efforts to promote vaccination. The researchers emphasize the need for continuous monitoring and the development of innovative strategies to maintain high vaccination rates. Future initiatives could include public health campaigns to improve vaccine literacy and address hesitancy, integrating seasonal vaccination efforts with broader pandemic preparedness strategies, and introducing organizational improvements to simplify vaccination processes.
Addressing logistical barriers, such as streamlining appointment scheduling, ensuring vaccine availability, and minimizing out-of-pocket costs, could also play a vital role in enhancing vaccine uptake. This research highlights the need for proactive and sustained approaches to safeguard public health through improved vaccination practices.
About the publication
Del Riccio, M., et al. A Missed Opportunity? Exploring Changes in Influenza Vaccination Coverage During the COVID-19 Pandemic: Data from 12 Countries Worldwide. Influenza and Other Respiratory Viruses. 2025; 19:e70057.
