11 November 2021

Chella van der Post and  Francesco Ciompi, theme Tumours of the digestive tract, received a grant from the Hanarth foundation for their research project to develop artificial intelligence (AI)  to improve histopathological detection of hereditary diffuse gastric cancer (DGC). 

Within this project ''Unmasking the invisible cancer: digital detection of diffuse-type gastric carcinomas'', they will develop AI methods to refine DGC diagnostics. Since DGC may be easily missed or hard to find on biopsies and prophylactic hereditary gastrectomy specimens, AI will aid the pathologist in the diagnostic work-up, improving the detection of relevant cell types among a very large set of slides, with high potential to improve cancer diagnostics. Furthermore, the automation in cell detection provided by AI algorithms will allow to quantitatively and objectively assess DGC patterns in large series of slides, potentially giving new insights in specific morphological  features of DGC, such as patterns of spatial cell distributions.

With this project, researchers aim at using AI to better identify and classify future patients with HDGC,  to increase detection of individual patients and families, that might eventually result in better patient stratification for therapeutic options and clinical decisions. This will give more insight into specific features of CDH1 mutated DGC, both in a hereditary as well as sporadic setting. In the end, researchers  aim to give public access to developed AI  technology for research purpose.

Related news items


Royal decorations for Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar

28 April 2021 Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar are appointed by His Majesty as Knight in the Order of the Dutch Lion, a highly prestigious decoration on 26 April 2021. read more

Awarded KWF grants for Radboudumc researchers

18 December 2019 KWF is investing 2.7 million euros in five different studies at Radboudumc. The awards are part of the new round of funding by DCS, in which over 34 million euros will be granted to Dutch cancer research. We congratulate our researchers with this funding and wish them success with their great work. read more

Exploration meeting Academic Alliance on Oncology

2 December 2019 Within the Academic Alliance, the Maastricht UMC+ and Radboudumc are already working together in several areas. And this is happening in more and more fields. On 27 November researchers from both umc's met during the fourth Exploration meeting, this time with the theme: Oncology. read more

KWF Roadshow 11 November 2019

10 October 2019 In which way(s) can KWF provide optimal support to oncological research and care? How can we maximize impact on our investments? These questions are pivotal in Ambition 2030: the vision that KWF developed in close cooperation with stakeholders in the oncological field. read more

Awarded KWF grants for Radboudumc researchers

2 July 2019 The Dutch Cancer Society (KWF) has awarded 25.5 million euros to 50 new research projects in 16 different institutes. 8 grants are awarded to Radboudumc researchers. We congratulate our researchers with this funding and wish them success with their great work. read more

Internal KWF review procedure 2020

13 June 2019 In agreement with the existing policy the research board and Radboud Center for Oncology have decided to continue with the mandatory internal review procedure for KWF grant applications. read more