Michiel Vermeulen, theme Cancer development and immune defense, received a 300,000 EUR grant within the NWO open call - GROOT consortium. In this project the Vermeulen lab will use cutting-edge mass spectrometry-based proteomics and interaction proteomics applications to study proteome and gene expression dynamics during early C. Elegans development.
In the NWO Open Competition Domain Science - GROOT researchers can apply as a part of a consortium for curiosity-driven, fundamental research in the research fields of the NWO Domain Science.
About the project: Single Cell Analysis of Animal Development
The cells of our body all contain an identical and complete manual for our life processes and body functions. Despite this identical genetic information, cells develop in highly divergent directions; some remain stem cells while others become, for instance, specialized neurons or muscle cells. How does a cell decide which direction to take? A team of world-leading researchers with divergent expertise will collaborate closely to answer this question. Starting from detailed molecular characterizations of individual cells in developing tissues, a predictive computer model will be created, which ultimately will reveal opportunities for improved tissue regeneration and cancer treatment.