NL
DE
6 January 2020
Lower respiratory tract infections (LRTI), such as pneumonia, are a leading cause of death especially in children below the age of 5 years. Low and middle-income countries (LMIC) have the highest burden of childhood pneumonia. Most LRTIs are caused by viruses, but differentiating viral from bacterial causes is mostly impossible due to the lack of accurate diagnostics. As a consequence, most cases are treated empirically leading to overuse and misuse of antibiotics, which is an important driver of the global epidemic of antimicrobial resistance. In this project a newly developed diagnostic device, which is based on the entrapment of aerosols from the lower respiratory tract will be used to identify the etiological agent in children with LRTI.
Lower respiratory tract infections (LRTI), such as pneumonia, are a leading cause of death especially in children below the age of 5 years. Low and middle-income countries (LMIC) have the highest burden of childhood pneumonia. Most LRTIs are caused by viruses, but differentiating viral from bacterial causes is mostly impossible due to the lack of accurate diagnostics. As a consequence, most cases are treated empirically leading to overuse and misuse of antibiotics, which is an important driver of the global epidemic of antimicrobial resistance. In this project a newly developed diagnostic device, which is based on the entrapment of aerosols from the lower respiratory tract will be used to identify the etiological agent in children with LRTI.
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