27 August 2018
Editorial article: link.
The article provides evidence that the anti-inflammatory ubiquitin editing enzyme TNFα induced protein 3 (TNFAIP3), also known as A20, acts as a master switch for the expression of IL-17A in human CD4+ T cells derived from Inflammatory Bowel disease (IBD) patients. Due its relevance in the field a JACI editorial article was also published highlighting Urbano and Koenen’s findings. ArticleTNF-α-induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade-driven IL-17A expression.
Paulo Urbano and Hans Koenen are member of the theme Inflammatory diseases.
Paulo Urbano and Hans Koenen, theme Inflammatory diseases, recently published an article in the Journal of Allergy and Clinical Immunology (JACI).
Publication in J Allergy Clin Immunol.: link.Editorial article: link.
The article provides evidence that the anti-inflammatory ubiquitin editing enzyme TNFα induced protein 3 (TNFAIP3), also known as A20, acts as a master switch for the expression of IL-17A in human CD4+ T cells derived from Inflammatory Bowel disease (IBD) patients. Due its relevance in the field a JACI editorial article was also published highlighting Urbano and Koenen’s findings. ArticleTNF-α-induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade-driven IL-17A expression.
Paulo Urbano and Hans Koenen are member of the theme Inflammatory diseases.
-
Want to know more about these subjects? Click on the buttons below for more news.
Related news items
Dutch Society of Clinical Chemistry Science & Innovation Award for the team of Hans Jacobs
14 June 2022 The team of Hans Jacobs pioneers on the development of personalized diagnostics to measure minimal residual disease in patients with multiple myeloma. read moreJoyce Aarts and colleagues published in Scientific Reports about the role of TGF-β1 in (experimental) arthritis
30 March 2022Joyce Aarts, theme Inflammatory diseases, and her colleagues published in Scientific Reports, that local inhibition of TGF-β1 signaling improves Th17/Treg balance but not joint pathology during experimental arthritis.
read more