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The underlying molecular mechanisms of PKC signaling in B cells are only partially resolved. Malou Zuidscherwoude and Vera Dunlock, group of Annemiek van Spriel, Dept. of Tumor Immunology, theme Cancer development and immune defense, now discovered that in response to B cell receptor stimulation, PKCb was specifically recruited to plasma membrane microdomains containing tetraspanin CD53.
Publication in Science Signaling
Malou Zuidscherwoude Vera Dunlock
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